Brian MacKenna
Director of NHS Service Analytics
Brian is Director of NHS Service Analytics at the Bennett Institute. He also works for NHS England as a pharmacist adviser and primary care medicines data clinical lead. Brian was previously Clinical Fellow to the English Chief Pharmaceutical Officer, Dr. Keith Ridge, and Deputy Head of Medicines Optimisation at Islington Clinical Commissioning Group. Brian previously worked in a variety of hospitals, in London and Australia. He has also completed his Masters in Public Health at King’s College and has a specialist interest in pharmacomedy.
Papers by Brian MacKenna
- Comparative safety and effectiveness of Pfizer BA.4-5 versus Sanofi during the spring 2023 COVID-19 booster vaccination programme in England: a matched cohort study in OpenSAFELY-TPP
- Changes in opioid prescribing during the COVID-19 pandemic in England: cohort study of 20 million patients in OpenSAFELY-TPP
- OpenSAFELY: Measuring BMI in 22 million patients in England
- OpenSAFELY: a platform for analysing electronic health records designed for reproducible research
- Trends in inequalities in avoidable hospitalisations across the COVID-19 pandemic: a cohort study of 23.5 million people in England
- Educational interventions delivered to prescribing advisers to influence primary care prescribing: a very low-cost pragmatic randomised trial using routine data from OpenPrescribing.net
- Consistency, completeness and external validity of ethnicity recording in NHS primary care records: a cohort study in 25 million patients’ records at source using OpenSAFELY
- Clinical and health inequality risk factors for non-COVID-related sepsis during the global COVID-19 pandemic: a national case-control and cohort study
- Interpreting Pathology Test Result Values With Comparators (<, >) in Electronic Health Records research: an OpenSAFELY short data report
- Antibiotics for Common Infections in Primary Care Before, During and after the COVID-19 Pandemic and Extent of Risk-Based Prescribing: Need for Personalised Guidelines
- Group A streptococcal cases and treatments during the COVID-19 pandemic and 2022 outbreak: a retrospective cohort study in England using OpenSAFELY-TPP
- The impact of the COVID-19 pandemic on the treatment of common infections in primary care and the change to antibiotic prescribing in England
- Fit notes associated with COVID-19 in 24 million patients’ primary care records: A cohort study in OpenSAFELY-TPP.
- The impact of COVID-19 on medication reviews in English primary care. An OpenSAFELY-TPP analysis of 20 million adult electronic health records.
- The impact of the COVID-19 pandemic on Antipsychotic Prescribing
- Impact of COVID-19 on recorded blood pressure screening and hypertension management in England: An analysis of monthly changes in Quality and Outcomes Framework indicators in OpenSAFELY
- Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults’ primary care records in England through OpenSAFELY
- Evaluation of the impact of COVID-19 pandemic on hospital admission related to common infections
- Repeated antibiotic exposure and risk of hospitalisation and death following COVID-19 infection (OpenSAFELY): a matched case–control study
- Data-driven identification of potentially successful intervention implementations: a proof of concept using five years of opioid prescribing data from over 7000 practices in England
- DMARD monitoring during the COVID-19 pandemic
- Changes in medication safety indicators in England throughout the covid-19 pandemic using OpenSAFELY: population based, retrospective cohort study of 57 million patients using federated analytics
- Impact of COVID-19 on broad-spectrum antibiotic prescribing for common infections in primary care in England: a time-series analyses using OpenSAFELY and effects of predictors including deprivation
- The impact of COVID-19 on antibiotic prescribing in primary care in England: Evaluation and risk prediction of appropriateness of type and repeat prescribing
- Challenges in Estimating the Effectiveness of COVID-19 Vaccination Using Observational Data
- Changes in COVID-19-related mortality across key demographic and clinical subgroups in England from 2020 to 2022: a retrospective cohort study using the OpenSAFELY platform
- Data-Driven Identification of Unusual Prescribing Behavior: Analysis and Use of an Interactive Data Tool Using 6 Months of Primary Care Data From 6500 Practices in England
- Comparative effectiveness of BNT162b2 versus mRNA-1273 covid-19 vaccine boosting in England: matched cohort study in OpenSAFELY-TPP
- First dose COVID-19 vaccine coverage amongst adolescents and children in England: an analysis of 3.21 million patients' primary care records in situ using OpenSAFELY
- Identifying Patterns of Clinical Interest in Clinicians' Treatment Preferences: Hypothesis-free Data Science Approach to Prioritizing Prescribing Outliers for Clinical Review
- Impact of Electronic Health Record Interface Design on Unsafe Prescribing of Ciclosporin, Tacrolimus, and Diltiazem: Cohort Study in English National Health Service Primary Care
- Suboptimal prescribing behaviour associated with clinical software design features: a retrospective cohort study in English NHS primary care
- OpenSAFELY: Do adults prescribed Non-steroidal anti-inflammatory drugs have an increased risk of death from COVID-19?
- Prescription of suboptimal statin treatment regimens: a retrospective cohort study of trends and variation in English primary care
- The NHS deserves better use of hospital medicines data
- Trends and variation in unsafe prescribing of methotrexate: a cohort study in English NHS primary care.
- Six months on – NHS England needs to focus on dissemination, implementation and audit of its Low-Priority Initiative
Blog posts by Brian MacKenna
- Understanding Repeat Antibiotic Prescribing in the Pandemic: Insights On Health Inequalities
- OpenSAFELY NHS Service Analytics
- Difference between BNF, dm+d and SNOMED CT codes
- Biologic Medicines for Severe Asthma
- NHS Dictionary of medicines and devices (dm+d): primary care prescribing of "hospital only" medicines
- How I use OpenPrescribing in my practice as a GP
- Your Organisation's OpenPrescribing Custom Email Alerts
- Impact of COVID-19 on prescribing in English general practice: March 2020
- What are the most commonly prescribed medicines? Top 10 prescribed medicines in NHS England primary care for 2019
- Changes to NHS medicines data: a rapid analysis from the Bennett Institute
- NHS England Investment and Impact Fund — A new dashboard on OpenPrescribing
- OpenPrescribing.yourcountry
- Greener NHS Prescribing Dashboards
- High Dose Dexamethasone
- Primary Care Networks (PCN) Dashboards — A new prescribing dashboard on OpenPrescribing
- New Measure — Inhalers and the Environment
- New Measure: Seven Day Prescribing for Long-term Conditions
- Zuclopenthixol Acetate: a new kind of measure on OpenPrescribing
- NHS dm+d browser — A New Feature on OpenPrescribing
- What is the dm+d? The NHS Dictionary of Medicines and Devices
- Custom Organisation Groupings: OpenPrescribing Plan for Organisations like Primary Care Networks
- All England Alerts : A New Feature on OpenPrescribing
- Openness and Transparency: why is openness and transparency important for good data analysis and how does OpenPrescribing embody it?
- NHS price concessions cost charities and local authorities an additional £5.6 million last year
- NHS Regional and STP Dashboards — A new Feature on OpenPrescribing
- Building new prescribing measures - we need your help
- Ghost Branded Generics - How to fix it
- NHS Price Concession Alerts — A new feature on OpenPrescribing
- Ghost Branded Generics - Positive News!
- Ghost Branded Generics: A new dashboard on OpenPrescribing
- Price Concessions Calculator — A New Feature on OpenPrescribing
- Phenytoin Supply Disruption Alert
- All England Dashboard - A New Feature on OpenPrescribing.net