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COMPare: a prospective cohort study correcting and monitoring 58 misreported trials in real time.
Identifying discrepancies in trial reporting in high-impact medical journals
Categories
- Research Integrity
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COMPare: Qualitative analysis of researchers' responses to critical correspondence on a cohort of 58 misreported trials
Responses to correspondence highlighting discrepancies in trials reporting
Categories
- Research Integrity
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Do doctors in dispensing practices with a financial conflict of interest prescribe more expensive drugs? A cross-sectional analysis of English primary care prescribing data.
Reducing antibiotic overuse is a key NHS priority. The majority of antibiotics are prescribed in primary care
Categories
- OpenPrescribing
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Measuring the Impact of an Open Web-Based Prescribing Data Analysis Service on Clinical Practice: Cohort Study on NHS England Data
Measuring the impact of OpenPrescribing being viewed on subsequent prescribing.
Categories
- OpenPrescribing
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Why did some practices not implement new antibiotic prescribing guidelines on urinary tract infection? A cohort study and survey in NHS England primary care
Describing trends and geographical variation in prescribing of trimethoprim and nitrofurantoin to treat urinary tract infections
Categories
- OpenPrescribing
- Policy Insights
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Opioid prescribing trends and geographical variation in England, 1998–2018: a retrospective database study
Our findings support calls for greater action to promote best practice in chronic pain prescribing and to reduce geographical variation.
Categories
- OpenPrescribing
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Six months on – NHS England needs to focus on dissemination, implementation and audit of its Low-Priority Initiative
JRSM letter
Categories
- OpenPrescribing
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Temporal trends in use of tests in UK primary care, 2000-15: retrospective analysis of 250 million tests
BMJ Tests in primary care paper
Categories
- OpenPathology
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Too few trials or too few reported trials?
Highlighting that there is a serious ongoing issue with the results of completed trials not being reported.
Categories
- Policy Insights
- TrialsTracker
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Time trends and geographical variation in prescribing of antibiotics in England 1998–2017
Despite a general trend towards more optimal antibiotic prescribing, considerable geographical variation persists across England's practices and CCGs.
Categories
- OpenPrescribing
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Compliance with requirement to report results on the EU Clinical Trials Register: cohort study and web resource.
Assessing compliance rates with the European Commission's requirement that all trials on the EU Clinical Trials Register (EUCTR) post results to the registry within 12 months of completion
Categories
- TrialsTracker
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Reply to Comment on 'Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis'
Replying to comment on paper: 'Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis'
Categories
- OpenPrescribing
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Why Cochrane should prioritise sharing data
Discussing Cochrane's practice on data sharing.
Categories
- Open Working
- Policy Insights
- Research Integrity
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Detecting Change in Comparison to Peers in NHS Prescribing Data: a Novel Application of Cumulative Sum Methodology
The CUSUM method appears to effectively discriminate between random noise and sustained change in prescribing behaviour. This method aims to allow practices and CCGs to be informed of important changes quickly, with a view to improve their prescribing behaviour.
Categories
- OpenPrescribing
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Pregabalin: what the patent litigation means for doctors and drug companies
Explaining the arguments over the Pregabalin patent case and explore the wider implications for the NHS and drug development
Categories
- OpenPrescribing
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The clinician impact and financial cost to the NHS of litigation over pregabalin: a cohort study in English primary care
Describing the variation in prescribing of pregabalin as branded Lyrica, geographically and over time
Categories
- OpenPrescribing
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Trends and variation in prescribing of low-priority treatments identified by NHS England: a cross-sectional study and interactive data tool in English primary care
Prescribing of low-value treatments is extensive but varies widely by treatment, geographic area and individual practice. Despite a fall in prescription numbers, the overall cost of prescribing for low-value items has risen.
Categories
- OpenPrescribing
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Time trends and geographical variation in prescribing of drugs for diabetes in England from 1998 to 2017
Our findings strongly support the case for comparative effectiveness trials of current diabetes drugs.
Categories
- OpenPrescribing
