Papers

Spotlight

[PRE-PRINT] Association between living with children and outcomes from COVID-19: an OpenSAFELY cohort study of 12 million adults in England
[PRE-PRINT] Association between living with children and outcomes from COVID-19: an OpenSAFELY cohort study of 12 million adults in England
03 November, 2020
Impact of Electronic Health Record Interface Design on Unsafe Prescribing of Ciclosporin, Tacrolimus, and Diltiazem: Cohort Study in English National Health Service Primary Care
Impact of Electronic Health Record Interface Design on Unsafe Prescribing of Ciclosporin, Tacrolimus, and Diltiazem: Cohort Study in English National Health Service Primary Care
16 October, 2020
[PRE-PRINT]Study protocol: Comparison of different risk prediction modelling approaches for COVID-19 related death using the OpenSAFELY platform
[PRE-PRINT]Study protocol: Comparison of different risk prediction modelling approaches for COVID-19 related death using the OpenSAFELY platform
15 October, 2020
Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids: an observational cohort study using the OpenSAFELY platform
Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids: an observational cohort study using the OpenSAFELY platform
24 September, 2020

OpenSAFELY

[PRE-PRINT] Association between living with children and outcomes from COVID-19: an OpenSAFELY cohort study of 12 million adults in England
[PRE-PRINT] Association between living with children and outcomes from COVID-19: an OpenSAFELY cohort study of 12 million adults in England
03 November, 2020
[PRE-PRINT]Study protocol: Comparison of different risk prediction modelling approaches for COVID-19 related death using the OpenSAFELY platform
[PRE-PRINT]Study protocol: Comparison of different risk prediction modelling approaches for COVID-19 related death using the OpenSAFELY platform
15 October, 2020
Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids: an observational cohort study using the OpenSAFELY platform
Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids: an observational cohort study using the OpenSAFELY platform
24 September, 2020
(PRE-PRINT) Ethnic differences in COVID-19 infection, hospitalisation, and mortality: an OpenSAFELY analysis of 17 million adults in England
(PRE-PRINT) Ethnic differences in COVID-19 infection, hospitalisation, and mortality: an OpenSAFELY analysis of 17 million adults in England
23 September, 2020
(PRE-PRINT) Hydroxychloroquine for prevention of COVID-19 mortality: a population-based cohort study
(PRE-PRINT) Hydroxychloroquine for prevention of COVID-19 mortality: a population-based cohort study
09 September, 2020
(PRE-PRINT) OpenSAFELY: Do adults prescribed Non-steroidal anti-inflammatory drugs have an increased risk of death from COVID-19?
(PRE-PRINT) OpenSAFELY: Do adults prescribed Non-steroidal anti-inflammatory drugs have an increased risk of death from COVID-19?
14 August, 2020
(PRE-PRINT) HIV infection and COVID-19 death: population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform
(PRE-PRINT) HIV infection and COVID-19 death: population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform
07 August, 2020
OpenSAFELY: factors associated with COVID-19 death in 17 million patients
OpenSAFELY: factors associated with COVID-19 death in 17 million patients
08 July, 2020
Better use of data and digital offer rapid opportunities to address covid-19
Better use of data and digital offer rapid opportunities to address covid-19
13 March, 2020

OpenPrescribing

Impact of Electronic Health Record Interface Design on Unsafe Prescribing of Ciclosporin, Tacrolimus, and Diltiazem: Cohort Study in English National Health Service Primary Care
Impact of Electronic Health Record Interface Design on Unsafe Prescribing of Ciclosporin, Tacrolimus, and Diltiazem: Cohort Study in English National Health Service Primary Care
16 October, 2020
Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids: an observational cohort study using the OpenSAFELY platform
Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids: an observational cohort study using the OpenSAFELY platform
24 September, 2020
Suboptimal prescribing behaviour associated with clinical software design features: a retrospective cohort study in English NHS primary care
Suboptimal prescribing behaviour associated with clinical software design features: a retrospective cohort study in English NHS primary care
27 August, 2020
Prescription of suboptimal statin treatment regimens: a retrospective cohort study of trends and variation in English primary care
Prescription of suboptimal statin treatment regimens: a retrospective cohort study of trends and variation in English primary care
30 July, 2020
The NHS deserves better use of hospital medicines data
The NHS deserves better use of hospital medicines data
17 July, 2020
Trends and variation in unsafe prescribing of methotrexate: a cohort study in English NHS primary care.
Trends and variation in unsafe prescribing of methotrexate: a cohort study in English NHS primary care.
29 June, 2020
Variation in responsiveness to warranted behaviour change among NHS clinicians: novel implementation of change detection methods in longitudinal prescribing data
Variation in responsiveness to warranted behaviour change among NHS clinicians: novel implementation of change detection methods in longitudinal prescribing data
02 October, 2019
Impact of Chief Medical Officer activity on prescribing of antibiotics in England: an interrupted time series analysis
Impact of Chief Medical Officer activity on prescribing of antibiotics in England: an interrupted time series analysis
20 April, 2019
Is Use of Homeopathy Associated With Poor Prescribing in English Primary Care? A Cross-Sectional Study
Is Use of Homeopathy Associated With Poor Prescribing in English Primary Care? A Cross-Sectional Study
18 April, 2019
Do doctors in dispensing practices with a financial conflict of interest prescribe more expensive drugs? A cross-sectional analysis of English primary care prescribing data.
Do doctors in dispensing practices with a financial conflict of interest prescribe more expensive drugs? A cross-sectional analysis of English primary care prescribing data.
05 February, 2019
Measuring the Impact of an Open Web-Based Prescribing Data Analysis Service on Clinical Practice: Cohort Study on NHS England Data
Measuring the Impact of an Open Web-Based Prescribing Data Analysis Service on Clinical Practice: Cohort Study on NHS England Data
16 January, 2019
Why did some practices not implement new antibiotic prescribing guidelines on urinary tract infection? A cohort study and survey in NHS England primary care
Why did some practices not implement new antibiotic prescribing guidelines on urinary tract infection? A cohort study and survey in NHS England primary care
22 December, 2018
Opioid prescribing trends and geographical variation in England, 1998–2018: a retrospective database study
Opioid prescribing trends and geographical variation in England, 1998–2018: a retrospective database study
20 December, 2018
Six months on – NHS England needs to focus on dissemination, implementation and audit of its Low-Priority Initiative
Six months on – NHS England needs to focus on dissemination, implementation and audit of its Low-Priority Initiative
03 December, 2018
Time trends and geographical variation in prescribing of antibiotics in England 1998–2017
Time trends and geographical variation in prescribing of antibiotics in England 1998–2017
15 September, 2018
Reply to Comment on ‘Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis”
Reply to Comment on ‘Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis”
21 August, 2018
Detecting Change in Comparison to Peers in NHS Prescribing Data: a Novel Application of Cumulative Sum Methodology
Detecting Change in Comparison to Peers in NHS Prescribing Data: a Novel Application of Cumulative Sum Methodology
09 July, 2018
The clinician impact and financial cost to the NHS of litigation over pregabalin: a cohort study in English primary care
The clinician impact and financial cost to the NHS of litigation over pregabalin: a cohort study in English primary care
07 June, 2018
Pregabalin: what the patent litigation means for doctors and drug companies
Pregabalin: what the patent litigation means for doctors and drug companies
07 June, 2018
Trends and variation in prescribing of low-priority treatments identified by NHS England: a cross-sectional study and interactive data tool in English primary care
Trends and variation in prescribing of low-priority treatments identified by NHS England: a cross-sectional study and interactive data tool in English primary care
22 May, 2018
Time trends and geographical variation in prescribing of drugs for diabetes in England from 1998 to 2017
Time trends and geographical variation in prescribing of drugs for diabetes in England from 1998 to 2017
07 May, 2018
Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis
Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis
23 April, 2018
Trends, geographical variation and factors associated with prescribing of gluten-free foods in English primary care: a cross-sectional study
Trends, geographical variation and factors associated with prescribing of gluten-free foods in English primary care: a cross-sectional study
16 April, 2018
OpenPrescribing: normalised data and software tool to research trends in English NHS primary care prescribing 1998–2016
OpenPrescribing: normalised data and software tool to research trends in English NHS primary care prescribing 1998–2016
28 February, 2018
New mechanism to identify cost savings in English NHS prescribing: minimising ‘price per unit’, a cross-sectional study
New mechanism to identify cost savings in English NHS prescribing: minimising ‘price per unit’, a cross-sectional study
08 February, 2018

OpenPathology

Better use of data and digital offer rapid opportunities to address covid-19
Better use of data and digital offer rapid opportunities to address covid-19
13 March, 2020
Practice variation in the use of tests in UK primary care: a retrospective analysis of 16 million tests performed over 3.3 million patient years in 2015/16
Practice variation in the use of tests in UK primary care: a retrospective analysis of 16 million tests performed over 3.3 million patient years in 2015/16
20 December, 2019
Optimising laboratory monitoring of chronic conditions in primary care: a quality improvement framework
Optimising laboratory monitoring of chronic conditions in primary care: a quality improvement framework
29 March, 2019
Temporal trends in use of tests in UK primary care, 2000-15: retrospective analysis of 250 million tests
Temporal trends in use of tests in UK primary care, 2000-15: retrospective analysis of 250 million tests
28 November, 2018
Variation in diagnostic test requests and outcomes: a preliminary metric for OpenPathology.net
Variation in diagnostic test requests and outcomes: a preliminary metric for OpenPathology.net
19 March, 2018

TrialsTracker

How we learnt to stop worrying and love web scraping
How we learnt to stop worrying and love web scraping
08 September, 2020
Compliance with legal requirement to report clinical trial results on ClinicalTrials.gov: a cohort study
Compliance with legal requirement to report clinical trial results on ClinicalTrials.gov: a cohort study
17 January, 2020
Why researchers should share their analytic code
Why researchers should share their analytic code
21 November, 2019
[PRE-PRINT] FDAAA TrialsTracker: A live informatics tool to monitor compliance with FDA requirements to report clinical trial results
[PRE-PRINT] FDAAA TrialsTracker: A live informatics tool to monitor compliance with FDA requirements to report clinical trial results
18 October, 2019
Personalised Medicine Using N-of-1 Trials: Overcoming Barriers to Delivery
Personalised Medicine Using N-of-1 Trials: Overcoming Barriers to Delivery
04 September, 2019
Catalogue of bias: publication bias.
Catalogue of bias: publication bias.
24 April, 2019
COMPare: a prospective cohort study correcting and monitoring 58 misreported trials in real time.
COMPare: a prospective cohort study correcting and monitoring 58 misreported trials in real time.
14 February, 2019
COMPare: Qualitative analysis of researchers' responses to critical correspondence on a cohort of 58 misreported trials
COMPare: Qualitative analysis of researchers' responses to critical correspondence on a cohort of 58 misreported trials
14 February, 2019
Too few trials or too few reported trials?
Too few trials or too few reported trials?
19 October, 2018
Compliance with requirement to report results on the EU Clinical Trials Register: cohort study and web resource.
Compliance with requirement to report results on the EU Clinical Trials Register: cohort study and web resource.
12 September, 2018
Why Cochrane should prioritise sharing data
Why Cochrane should prioritise sharing data
30 July, 2018
Noncommercial Funders' Policies on Trial Registration, Access to Summary Results, and Individual Patient Data Availability.
Noncommercial Funders' Policies on Trial Registration, Access to Summary Results, and Individual Patient Data Availability.
24 April, 2018
A cross-sectional study of all clinicians' conflict of interest disclosures to NHS hospital employers in England 2015-2016.
A cross-sectional study of all clinicians' conflict of interest disclosures to NHS hospital employers in England 2015-2016.
19 March, 2018
Prevalence of clinical trial status discrepancies: A cross-sectional study of 10,492 trials registered on both ClinicalTrials.gov and the European Union Clinical Trials Register.
Prevalence of clinical trial status discrepancies: A cross-sectional study of 10,492 trials registered on both ClinicalTrials.gov and the European Union Clinical Trials Register.
07 March, 2018
Pharmaceutical companies' policies on access to trial data, results, and methods: audit study.
Pharmaceutical companies' policies on access to trial data, results, and methods: audit study.
26 July, 2017
The WHO joint statement from funders on trials transparency
The WHO joint statement from funders on trials transparency
19 June, 2017
The TrialsTracker: Automated ongoing monitoring of failure to share clinical trial results by all major companies and research institutions.
The TrialsTracker: Automated ongoing monitoring of failure to share clinical trial results by all major companies and research institutions.
03 November, 2016
OpenTrials: towards a collaborative open database of all available information on all clinical trials
OpenTrials: towards a collaborative open database of all available information on all clinical trials
08 April, 2016
Make journals report clinical trials properly
Make journals report clinical trials properly
04 February, 2016
Fixing flaws in science must be professionalized
Fixing flaws in science must be professionalized
01 February, 2016
Antivirals, pandemic planning, and failure to heed calls for trial data
Antivirals, pandemic planning, and failure to heed calls for trial data
22 October, 2015
How medicine is broken, and how we can fix it
How medicine is broken, and how we can fix it
23 June, 2015
How to get all trials reported: audit, better data, and individual accountability
How to get all trials reported: audit, better data, and individual accountability
14 April, 2015

DataLab Policy Insights

Impact of Electronic Health Record Interface Design on Unsafe Prescribing of Ciclosporin, Tacrolimus, and Diltiazem: Cohort Study in English National Health Service Primary Care
Impact of Electronic Health Record Interface Design on Unsafe Prescribing of Ciclosporin, Tacrolimus, and Diltiazem: Cohort Study in English National Health Service Primary Care
16 October, 2020
Suboptimal prescribing behaviour associated with clinical software design features: a retrospective cohort study in English NHS primary care
Suboptimal prescribing behaviour associated with clinical software design features: a retrospective cohort study in English NHS primary care
27 August, 2020
The NHS deserves better use of hospital medicines data
The NHS deserves better use of hospital medicines data
17 July, 2020
Bringing NHS data analysis into the 21st century
Bringing NHS data analysis into the 21st century
16 July, 2020
Better use of data and digital offer rapid opportunities to address covid-19
Better use of data and digital offer rapid opportunities to address covid-19
13 March, 2020
The poor performance of apps assessing skin cancer risk
The poor performance of apps assessing skin cancer risk
10 February, 2020
Compliance with legal requirement to report clinical trial results on ClinicalTrials.gov: a cohort study
Compliance with legal requirement to report clinical trial results on ClinicalTrials.gov: a cohort study
17 January, 2020
Barriers to Working With National Health Service England’s Open Data
Barriers to Working With National Health Service England’s Open Data
13 January, 2020
Why researchers should share their analytic code
Why researchers should share their analytic code
21 November, 2019
[PRE-PRINT] FDAAA TrialsTracker: A live informatics tool to monitor compliance with FDA requirements to report clinical trial results
[PRE-PRINT] FDAAA TrialsTracker: A live informatics tool to monitor compliance with FDA requirements to report clinical trial results
18 October, 2019
Why did some practices not implement new antibiotic prescribing guidelines on urinary tract infection? A cohort study and survey in NHS England primary care
Why did some practices not implement new antibiotic prescribing guidelines on urinary tract infection? A cohort study and survey in NHS England primary care
22 December, 2018
Too few trials or too few reported trials?
Too few trials or too few reported trials?
19 October, 2018
Why Cochrane should prioritise sharing data
Why Cochrane should prioritise sharing data
30 July, 2018
Noncommercial Funders' Policies on Trial Registration, Access to Summary Results, and Individual Patient Data Availability.
Noncommercial Funders' Policies on Trial Registration, Access to Summary Results, and Individual Patient Data Availability.
24 April, 2018
Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis
Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis
23 April, 2018
A cross-sectional study of all clinicians' conflict of interest disclosures to NHS hospital employers in England 2015-2016.
A cross-sectional study of all clinicians' conflict of interest disclosures to NHS hospital employers in England 2015-2016.
19 March, 2018
Make journals report clinical trials properly
Make journals report clinical trials properly
04 February, 2016
Fixing flaws in science must be professionalized
Fixing flaws in science must be professionalized
01 February, 2016
Antivirals, pandemic planning, and failure to heed calls for trial data
Antivirals, pandemic planning, and failure to heed calls for trial data
22 October, 2015
How medicine is broken, and how we can fix it
How medicine is broken, and how we can fix it
23 June, 2015
How to get all trials reported: audit, better data, and individual accountability
How to get all trials reported: audit, better data, and individual accountability
14 April, 2015

Research Integrity

How we learnt to stop worrying and love web scraping
How we learnt to stop worrying and love web scraping
08 September, 2020
Why researchers should share their analytic code
Why researchers should share their analytic code
21 November, 2019
Catalogue of bias: publication bias.
Catalogue of bias: publication bias.
24 April, 2019
COMPare: Qualitative analysis of researchers' responses to critical correspondence on a cohort of 58 misreported trials
COMPare: Qualitative analysis of researchers' responses to critical correspondence on a cohort of 58 misreported trials
14 February, 2019
COMPare: a prospective cohort study correcting and monitoring 58 misreported trials in real time.
COMPare: a prospective cohort study correcting and monitoring 58 misreported trials in real time.
14 February, 2019
Why Cochrane should prioritise sharing data
Why Cochrane should prioritise sharing data
30 July, 2018
Noncommercial Funders' Policies on Trial Registration, Access to Summary Results, and Individual Patient Data Availability.
Noncommercial Funders' Policies on Trial Registration, Access to Summary Results, and Individual Patient Data Availability.
24 April, 2018
A cross-sectional study of all clinicians' conflict of interest disclosures to NHS hospital employers in England 2015-2016.
A cross-sectional study of all clinicians' conflict of interest disclosures to NHS hospital employers in England 2015-2016.
19 March, 2018
Pharmaceutical companies' policies on access to trial data, results, and methods: audit study.
Pharmaceutical companies' policies on access to trial data, results, and methods: audit study.
26 July, 2017
The WHO joint statement from funders on trials transparency
The WHO joint statement from funders on trials transparency
19 June, 2017
Fixing flaws in science must be professionalized
Fixing flaws in science must be professionalized
01 February, 2016
How medicine is broken, and how we can fix it
How medicine is broken, and how we can fix it
23 June, 2015

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