OpenPrescribing papers

  1. Educational interventions delivered to prescribing advisers to influence primary care prescribing: a very low-cost pragmatic randomised trial using routine data from OpenPrescribing.net

    A low cost randomised trial of an educational intervention in CCGs to influence prescribing of low-priority items

    Status
    Preprint

    Categories

    • OpenPrescribing

  2. Data-driven identification of potentially successful intervention implementations: a proof of concept using five years of opioid prescribing data from over 7000 practices in England

    By applying one of our existing analysis tools to a national dataset, we were able to rank NHS organisations by reduction in opioid prescribing rates. Highly ranked organisations are candidates for further qualitative research into intervention design and implementation.

    Status
    Preprint

    Categories

    • OpenPrescribing

  3. Data-Driven Identification of Unusual Prescribing Behavior: Analysis and Use of an Interactive Data Tool Using 6 Months of Primary Care Data From 6500 Practices in England

    Data-driven approaches have the potential to overcome existing biases with regard to the planning and execution of audits, interventions, and policy making within NHS organizations, potentially revealing new targets for improved health care service delivery.

    Categories

    • OpenPrescribing

  4. Identifying Patterns of Clinical Interest in Clinicians' Treatment Preferences: Hypothesis-free Data Science Approach to Prioritizing Prescribing Outliers for Clinical Review

    A new method for prioritizing prescribing outliers for clinical review with discussion of two illustrative examples of anti-psychotics

    Categories

    • OpenPrescribing

  5. Impact of Electronic Health Record Interface Design on Unsafe Prescribing of Ciclosporin, Tacrolimus, and Diltiazem: Cohort Study in English National Health Service Primary Care

    JMIR EHR design paper

    Categories

    • OpenPrescribing
    • Policy Insights

  6. Suboptimal prescribing behaviour associated with clinical software design features: a retrospective cohort study in English NHS primary care

    EHR design paper

    Categories

    • OpenPrescribing
    • Research Integrity

  7. Prescription of suboptimal statin treatment regimens: a retrospective cohort study of trends and variation in English primary care

    BJGP statins paper

    Categories

    • OpenPrescribing

  8. The NHS deserves better use of hospital medicines data

    Hospitals Data BMJ Paper

    Categories

    • OpenPrescribing
    • Policy Insights

  9. Trends and variation in unsafe prescribing of methotrexate: a cohort study in English NHS primary care.

    Describing trends and geographical variation in methotrexate prescribing that breaches national safety recommendation

    Categories

    • OpenPrescribing

  10. Variation in responsiveness to warranted behaviour change among NHS clinicians: novel implementation of change detection methods in longitudinal prescribing data

    Determining how clinicians vary in their response to new guidance on existing or new interventions

    Categories

    • OpenPrescribing

  11. Impact of Chief Medical Officer activity on prescribing of antibiotics in England: an interrupted time series analysis

    Determining if there was a measurable impact from the 5 year antimicrobial resistance strategy on overall antibiotic prescribing in NHS primary care in England.

    Categories

    • OpenPrescribing

  12. Is Use of Homeopathy Associated With Poor Prescribing in English Primary Care? A Cross-Sectional Study

    Prescribing of homeopathy still occurs in a small minority of English general practices. We hypothesised that practices that prescribe any homeopathic preparations might differ in their prescribing of other drugs.

    Categories

    • OpenPrescribing

  13. Do doctors in dispensing practices with a financial conflict of interest prescribe more expensive drugs? A cross-sectional analysis of English primary care prescribing data.

    Reducing antibiotic overuse is a key NHS priority. The majority of antibiotics are prescribed in primary care

    Categories

    • OpenPrescribing

  14. Measuring the Impact of an Open Web-Based Prescribing Data Analysis Service on Clinical Practice: Cohort Study on NHS England Data

    Measuring the impact of OpenPrescribing being viewed on subsequent prescribing.

    Categories

    • OpenPrescribing

  15. Why did some practices not implement new antibiotic prescribing guidelines on urinary tract infection? A cohort study and survey in NHS England primary care

    Describing trends and geographical variation in prescribing of trimethoprim and nitrofurantoin to treat urinary tract infections

    Categories

    • OpenPrescribing
    • Policy Insights

  16. Opioid prescribing trends and geographical variation in England, 1998–2018: a retrospective database study

    Our findings support calls for greater action to promote best practice in chronic pain prescribing and to reduce geographical variation.

    Categories

    • OpenPrescribing

  17. Six months on – NHS England needs to focus on dissemination, implementation and audit of its Low-Priority Initiative

    JRSM letter

    Categories

    • OpenPrescribing

  18. Time trends and geographical variation in prescribing of antibiotics in England 1998–2017

    Despite a general trend towards more optimal antibiotic prescribing, considerable geographical variation persists across England's practices and CCGs.

    Categories

    • OpenPrescribing

  19. Reply to Comment on 'Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis'

    Replying to comment on paper: 'Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis'

    Categories

    • OpenPrescribing

  20. Detecting Change in Comparison to Peers in NHS Prescribing Data: a Novel Application of Cumulative Sum Methodology

    The CUSUM method appears to effectively discriminate between random noise and sustained change in prescribing behaviour. This method aims to allow practices and CCGs to be informed of important changes quickly, with a view to improve their prescribing behaviour.

    Categories

    • OpenPrescribing

  21. Pregabalin: what the patent litigation means for doctors and drug companies

    Explaining the arguments over the Pregabalin patent case and explore the wider implications for the NHS and drug development

    Categories

    • OpenPrescribing

  22. The clinician impact and financial cost to the NHS of litigation over pregabalin: a cohort study in English primary care

    Describing the variation in prescribing of pregabalin as branded Lyrica, geographically and over time

    Categories

    • OpenPrescribing

  23. Trends and variation in prescribing of low-priority treatments identified by NHS England: a cross-sectional study and interactive data tool in English primary care

    Prescribing of low-value treatments is extensive but varies widely by treatment, geographic area and individual practice. Despite a fall in prescription numbers, the overall cost of prescribing for low-value items has risen.

    Categories

    • OpenPrescribing

  24. Time trends and geographical variation in prescribing of drugs for diabetes in England from 1998 to 2017

    Our findings strongly support the case for comparative effectiveness trials of current diabetes drugs.

    Categories

    • OpenPrescribing

  25. Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis

    Measuring the uptake of tamoxifen, and the alternative raloxifene, in national prescribing data sets

    Categories

    • OpenPrescribing
    • Policy Insights

  26. Trends, geographical variation and factors associated with prescribing of gluten-free foods in English primary care: a cross-sectional study

    Gluten-free prescribing is in a state of flux, with substantial clinically unwarranted variation between practices and CCGs.

    Categories

    • OpenPrescribing

  27. OpenPrescribing: normalised data and software tool to research trends in English NHS primary care prescribing 1998–2016

    Publicly available data can be made accessible through interactive online tools to help researchers and policy-makers explore time trends in prescribing.

    Categories

    • OpenPrescribing

  28. New mechanism to identify cost savings in English NHS prescribing: minimising 'price per unit', a cross-sectional study

    We have developed a new method to identify and enable large potential cost savings within NHS community prescribing. Given the current pressures on the NHS, it is vital that these potential savings are realised.

    Categories

    • OpenPrescribing